J Vasc Res 1997 Jul-Aug;34(4):306-11 Related Articles, Books, LinkOut Combined physical therapy
for lymphedema evaluated by fluorescence microlymphography and lymph capillary pressure measurements.
Franzeck UK, Spiegel I, Fischer M, Bortzler C, Stahel HU, Bollinger A. Department of Medicine, University
Hospital, Zurich, Switzerland.
The treatment of patients with lymphedema is still controversial.
Combined physical therapy with manual lymph drainage and compression therapy is most frequently
used to reduce lymphatic leg swelling. However, objective evidence is rare that this empirical form
of treatment has a scientific basis. In a prospective study fluorescence microlymphography and pressure
measurements in cutaneous lymph capillaries were used to assess objectively the effect of combined
decongestive physical therapy on abnormal microlymphatic dynamics in lymphedema. 12 patients with
primary and secondary lymphedema were studied before treatment, after 2 weeks of intensive physical
therapy and 3 months of continuing compression and ergotherapy. After 2 weeks of intensive manual
lymph drainage and compression bandaging (phase 1) microlymphatic hypertension (12.8 +/- 5.7 mm
Hg) was significantly (p = 0.01) reduced to a mean lymph capillary pressure of 5.9 +/- 4.5 mm Hg.
More than 3 months later after continuing compression lymph capillary pressure (3.2 +/- 5.2 mm Hg)
was still significantly (p = 0.03) reduced. Simultaneously the maximum spread of the fluorescent
contrast medium in the superficial lymph capillary network decreased significantly (p = 0.01) from
21.3 +/- 14.3 to 11.3 +/- 4.8 mm. Accordingly the clinical condition improved, and the mean circumferences
of the forefoot and ankle were significantly (p < 0.05) reduced. Combined decongestive physical therapy
is an effective treatment for lymphedema which results in a normalization of microlymphatic hypertension
and an improvement of the clinical appearance.
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